"This gratifying success of the project means that we now have a powerful tool to further develop this new class of compounds through structure-based design. These crystal structures give us a molecular map for the development of new effective drug candidates,” says Dr. Thomas Olin, CEO, Kancera AB.
The objective of this project is to weaken the tumor by reducing its metabolism, in turn resulting in decreased tumor resistance to radiation and chemotherapy.
As recently announced in another of the Kancera preclinical projects, the research teams of Professor Mellstedt at the Karolinska Institutet, Kancera AB and iNovacia AB, have in collaboration developed synthetic small molecules that kill leukemic cells with a 25-fold higher selectivity compared to the cytotoxic drugs available on the market today.
Listing on First North and the ongoing Share Issue
The Board of Directors of Kancera has applied for listing of the Company’s shares on NASDAQ OMX First North. Provided the ongoing Offering is completed on January 31, it is anticipated that trading on First North will begin February 2011. Kancera is issuing 3,600,000 new shares. The issue price has been set at SEK 7 per share, which means that the issue will contribute SEK 25.2m to Kancera before issue expenses. For more information about the Offering and risk factors, please visit www.kancera.com.
About Kancera AB (publ)
Kancera AB is a biotech company focusing is on novel and effective treatment of leukaemia and solid tumors. The portfolio contains PFKFB3 inhibitors targeting glucose metabolism in solid tumors and ROR-1 inhibitors for the treatment of CLL and other hematological malignancies.
For further information, please contact
- Dr. Thomas Olin, CEO, +46 (0)735 204001
- Professor Håkan Mellstedt, +46 (0)706 589809
Kancera AB (publ)
SE 112 51 Stockholm
Please visit Kancera's homepage www.kancera.com